Systemic disparities place minority populations at the greatest risk of contracting and dying from Covid-19, and there is robust literature documenting how structural racism has adversely impacted the well-being of Black, Latinx, and Indigenous people. To date, the predominant focus has been on how disparities impact patients before and during hospitalization with Covid-19. However, disparities in the post-hospitalization period remain unaddressed. Specifically, patients recovering from Covid-19 are at risk for a host of physical, cognitive, and psychiatric sequelae of critical illness, collectively termed “post-intensive care syndrome (PICS).” In the present article, we review the literature on disparities in PICS, highlight the personal toll of Covid-19 on our patients, and suggest solutions to anticipated challenges. We outline a three-pronged approach involving (1) the prevention of critical illness, (2) the deployment of short-term post-hospitalization initiatives, and (3) the implementation of long-term post-hospitalization and community-based solutions.